Biodephyne

Modelling and filling medical device

Biodephyne

Biodephyne® is a filling and modelling solution for the dermal matrix based on hyaluronic acid and amino acids, indicated in the prevention and treatment of facial skin damage, such as dehydration and pigmentation.

It is an injectable, sterile and apyrogenic EU MDR CERTIFIED (Medical Device Regulation) medical device to be used for intradermal microinjection, which degrades slowly after implantation.

Its composition includes:

  • Hyaluronic acid fragments
  • Isoleucine, Leucine, Lysine
  • Proline, Valine, Glycine, Serine
  • Alanine, Cysteine
  • Phosphate buffer system

Biodephyne® is made up entirely of fragments of hyaluronic acid in the range between 20 and 38 monomers and precursor amino acids of collagen, elastin and glycosaminoglycans.

Amino acids are the building blocks of all proteins, including the most abundant fibrous proteins in the skin, as keratins, collagen and elastin. Sagging and wrinkled skin are features of chronic sun-damaged and aged uncared skin, and they are mainly associated with the deterioration of collagen and elastic fibers.

The maintenance of skin structures by self-repair processes is essential to skin health. Thus, amino acids significantly impact the appearance of the skin.

Amino acids are important nutrients required for:

  • wound healing promotion and repair of the damaged skin;
  • acid-base balance and water retention in cellular layers, such as stratum corneum;
  • protection against sunlight damage;
  • maintenance of an appropriate skin microbiome.

Recommended treatment areas

  • Glabellar area
  • Nasolabial folds
  • Zygomatic area
  • Perioral wrinkles
  • Submental area
  • Neck, Décolleté, Hands

(and all parts of the body that need biorevitalization)

Dosage

The maximum recommended dosage is 5 ml per treatment session.

Treatment duration

One session every 7 days, four times; one session every 15 days, twice.

Maintenance

One session per month.